Blar i forfatter "Hovd, Aud-Malin Karlsson"

Viser treff 1-5 av 5

    • Chip-based multimodal super-resolution microscopy for histological investigations of cryopreserved tissue sections 

      Villegas, Luis; Dubey, Vishesh Kumar; Nystad, Mona; Tinguely, Jean-Claude; Coucheron, David Andre; Dullo, Firehun Tsige; Priyadarshi, Anish; Acuna Maldonado, Sebastian Andres; Ahmad, Azeem; Mateos, Jose M.; Barmettler, Gery; Ziegler, Urs; Birgisdottir, Åsa Birna; Hovd, Aud-Malin Karlsson; Fenton, Kristin Andreassen; Acharya, Ganesh; Agarwal, Krishna; Ahluwalia, Balpreet Singh (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-24)
      Histology involves the observation of structural features in tissues using a microscope. While diffraction-limited optical microscopes are commonly used in histological investigations, their resolving capabilities are insufficient to visualize details at subcellular level. Although a novel set of super-resolution optical microscopy techniques can fulfill the resolution demands in such cases, the ...

    • The Immunostimulatory Potential of Mesenchymal Stem Cells for formation of Tertiary Lymphoid Structures in Lupus Nephritis 

      Hovd, Aud-Malin Karlsson (Master thesis; Mastergradsoppgave, 2017-05-15)
      Formation of tertiary lymphoid structures (TLS) occurs in tissues targeted by chronic inflammatory processes, such as infection and autoimmunity. In systemic lupus erythematosus (SLE), TLS have been observed in the kidneys of lupus-prone mice and in kidney biopsies of SLE patients with Lupus Nephritis (LN). Here the role of tissue-specific mesenchymal stem cells (MSCs) as lymphoid tissue organizer ...

    • Kidney tertiary lymphoid structures in Lupus Nephritis develop into large interconnected networks and resemble lymph nodes in gene signature 

      Dorraji, Seyed Esmaeil; Kanapathippillai, Premasany; Hovd, Aud-Malin Karlsson; Stenersrød, Mikael Ryan; Horvei, Kjersti Daae; Ursvik, anita; Figenschau, Stine; Thiyagarajan, Dhivya Borra; Fenton, Christopher Graham; Pedersen, Hege Lynum; Fenton, Kristin Andreassen (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-16)
      Immune aggregates organized as tertiary lymphoid structures (TLS) are observed within the kidneys of patients with systemic lupus erythematosus and lupus nephritis (LN). Renal TLS was characterized in lupus-prone New Zealand black × New Zealand white F1 mice analyzing cell composition and vessel formation. RNA sequencing was performed on transcriptomes isolated from lymph nodes, macrodissected TLS ...

    • Mesenchymal stem cells and T cells in the formation of Tertiary Lymphoid Structures in Lupus Nephritis 

      Dorraji, Seyed Esmaeil; Hovd, Aud-Malin Karlsson; Kanapathippillai, Premasany; Bakland, Gunnstein; Eilertsen, Gro Østli; Figenschau, Stine; Fenton, Kristin Andreassen (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-18)
      Tertiary lymphoid structures (TLS) develop in the kidneys of lupus-prone mice and systemic lupus erythematosus (SLE) patients with lupus nephritis (LN). Here we investigated the presence of mesenchymal stem cells (MSCs) in the development of TLS in murine LN, as well as the role of human MSCs as lymphoid tissue organizer (LTo) cells on the activation of CD4+ T cells from three groups of donors ...

    • Photonic-chip: a multimodal imaging tool for histopathology 

      Villegas, Luis; Dubey, Vishesh Kumar; Tinguely, Jean-Claude; Coucheron, David Andre; Priyadarshi, Anish; Acuña Maldonado, Sebastian Andres; Agarwal, Krishna; Mateos, Jose M; Nystad, Mona; Hovd, Aud-Malin Karlsson; Fenton, Kristin Andreassen; Ahluwalia, Balpreet Singh (Conference object; Konferansebidrag, 2021-04)
      We propose the photonic-chip as a multimodal imaging platform for histopathological assessment, allowing large fields-of-view across diverse microscopy methods including total internal reflection fluorescence and single-molecule localization.